Samara gained prominence with her role as Indi Walker in the Australian soap opera "Home and Away" (2009–2013), earning a nomination for Best Female Performance at the AACTA Awards in 2012.
She successfully transitioned to Hollywood, starring in films like "Ready or Not" (2019), which established her as a prominent figure in the horror-comedy genre.
She has been part of critically acclaimed ensemble casts, notably in "Three Billboards Outside Ebbing, Missouri" (2017), which won the Screen Actors Guild Award for Outstanding Performance by a Cast in a Motion Picture.